Hiroko Isoda Selected Research

caffeoylquinic acid

1/2020	3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes.
1/2019	3,4,5-Tricaffeoylquinic acid induces adult neurogenesis and improves deficit of learning and memory in aging model senescence-accelerated prone 8 mice.

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Hiroko Isoda Research Topics

Disease

16	Neoplasms (Cancer) 01/2022 - 12/2007
16	Leukemia 09/2014 - 01/2002
13	Melanoma (Melanoma, Malignant) 01/2020 - 12/2007
9	Breast Neoplasms (Breast Cancer) 01/2017 - 08/2002
8	Hypersensitivity (Allergy) 10/2013 - 01/2008
7	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2011
7	Neuroblastoma 01/2020 - 01/2011
6	Inflammation (Inflammations) 05/2022 - 01/2018
6	Body Weight (Weight, Body) 12/2021 - 04/2008
6	Experimental Melanoma 08/2021 - 05/2009
6	Fibrosis (Cirrhosis) 01/2020 - 10/2013
5	Insulin Resistance 06/2021 - 01/2011
4	Obesity 01/2019 - 01/2013
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 05/2012
3	Neuroinflammatory Diseases 01/2021 - 01/2019
3	Hypopigmentation (Hypomelanosis) 04/2020 - 03/2013
3	Type 2 Diabetes Mellitus (MODY) 01/2019 - 08/2015
3	Colonic Neoplasms (Colon Cancer) 11/2016 - 01/2013
2	Alopecia (Baldness) 01/2022 - 07/2021
2	Neoplasm Metastasis (Metastasis) 01/2020 - 08/2018
2	Cognitive Dysfunction 01/2020 - 10/2012
2	Non-alcoholic Fatty Liver Disease 11/2019 - 04/2018
2	Knee Osteoarthritis 01/2018 - 07/2017
2	Pain (Aches) 07/2017 - 11/2016
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 09/2014 - 01/2014
2	Pheochromocytoma 05/2012 - 09/2010
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 02/2022
1	Cerebral Small Vessel Diseases 02/2022
1	Hemorrhage 02/2022
1	Stroke (Strokes) 02/2022
1	Lacunar Stroke 02/2022
1	Cerebral Hemorrhage 02/2022
1	Sarcopenia 12/2021

Drug/Important Bio-Agent (IBA)

8	AntioxidantsIBA 01/2021 - 01/2011
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2008
7	Amyloid (Amyloid Fibrils)IBA 01/2017 - 01/2011
6	FlavonoidsIBA 01/2020 - 05/2011
5	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2013
5	Pharmaceutical PreparationsIBA 01/2022 - 11/2019
5	Biological ProductsIBA 01/2022 - 10/2009
5	EnzymesIBA 04/2020 - 01/2011
5	3-methylquercetinIBA 01/2020 - 01/2015
5	Insulin (Novolin)FDA Link 01/2020 - 08/2015
5	LipidsIBA 01/2019 - 01/2002
5	oleuropeinIBA 01/2019 - 01/2009
5	Triglycerides (Triacylglycerol)IBA 01/2018 - 04/2008
5	Hexosaminidases (Hexosaminidase)IBA 10/2013 - 10/2010
4	AcidsIBA 01/2022 - 03/2011
4	DiterpenesIBA 08/2018 - 05/2009
4	mezereinIBA 08/2018 - 05/2009
4	Monophenol Monooxygenase (Tyrosinase)IBA 01/2017 - 01/2013
4	3,4-dihydroxyphenylethanol (hydroxytyrosol)IBA 01/2015 - 04/2008
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2012
3	Neuroprotective AgentsIBA 01/2020 - 03/2011
3	CholesterolIBA 01/2020 - 04/2008
3	maslinic acidIBA 01/2018 - 11/2016
3	Ethanol (Ethyl Alcohol)IBA 01/2015 - 01/2013
3	acteosideIBA 10/2013 - 10/2010
2	CollagenIBA 05/2022 - 02/2016
2	Antidepressive Agents (Antidepressants)IBA 12/2021 - 01/2019
2	argan oilIBA 08/2021 - 01/2013
2	Anthocyanins (Anthocyanin)IBA 06/2021 - 01/2011
2	cyanidinIBA 06/2021 - 01/2011
2	LuteolinIBA 03/2021 - 01/2021
2	Amyloid beta-PeptidesIBA 01/2020 - 05/2011
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 08/2017
2	caffeoylquinic acidIBA 01/2020 - 01/2019
2	CytokinesIBA 01/2019 - 10/2012
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 01/2018
2	Cholinergic Agents (Cholinergics)IBA 01/2019 - 09/2010
2	2- (2- methoxy- 4- nitrophenyl)- 3- (4- nitrophenyl)- 5- (2,4- disulfophenyl)- 2H tetrazolium monosodium saltIBA 08/2017 - 11/2016
2	Melanins (Melanin)IBA 01/2017 - 12/2007
2	Hypoglycemic Agents (Hypoglycemics)IBA 05/2016 - 04/2016
2	LDL CholesterolIBA 10/2014 - 04/2008
2	ApigeninIBA 09/2014 - 02/2013
2	Therapeutic UsesIBA 01/2014 - 01/2011
2	olive leaf extractIBA 01/2014 - 05/2007
2	GenisteinIBA 12/2013 - 11/2002
2	Plant ExtractsIBA 10/2013 - 10/2009
2	Immunoglobulin E (IgE)IBA 10/2013 - 03/2011
2	Mitogen-Activated Protein KinasesIBA 10/2013 - 03/2013
2	PolyphenolsIBA 01/2013 - 05/2012
2	HDL CholesterolIBA 01/2013 - 04/2008
2	3,5-dicaffeoylquinic acidIBA 10/2012 - 01/2011
2	Olive OilIBA 08/2012 - 01/2009
2	Messenger RNA (mRNA)IBA 07/2012 - 01/2011
2	nitroxylIBA 11/2011 - 05/2011
2	fulvic acidIBA 03/2011 - 10/2009
2	beta-N-AcetylhexosaminidasesIBA 10/2009 - 05/2007
1	Keratins (Keratin)IBA 05/2022
1	Clopidogrel (Plavix)FDA Link 02/2022
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 02/2022
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 02/2022
1	Phosphodiesterase 3 InhibitorsIBA 02/2022
1	Minoxidil (Rogaine)FDA LinkGeneric 01/2022
1	serum P-component (CIt)IBA 12/2021
1	Phenylalanine (L-Phenylalanine)FDA Link 12/2021

Therapy/Procedure

8	Therapeutics 02/2022 - 07/2012
2	Oral Administration 11/2020 - 08/2018
2	Chemoprevention 12/2013 - 02/2013